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1、 K PK a 胶原 HK a a 选择通路 TF a a Ca2+Ca2+传统通路（大量）Ca2+a、a F1+2 a a Ca2+FPA/FPB fibrinogen FM Fbn aaPL+Ca2+aaPL+Ca2+2-AP:2-antiplasminFDPs:-acting as antithrombins -blocking fibrin polymerlization -producing a structurally defective fibrin polymer -impairing the platelet -clearing the functions of monocy
2、tes-macrophages Therefore,the presence of large amounts of FDP in the blood stream is a major factor in the induction of hemorrhage in a lot of patients suffered from DIC.Secondary fibrinolysis（coagulants disrupted,FDPs）Formation of small blood clotsDisruption of coagulation and bleeding tendencyCoa
3、gulants depleted,platelets ctivation of coagulation system,reduction of anticoagulationActivation of Coagulation System,Reduction of Anticoagulation）PlateletFibrinendotoxin,IC,thrombin,particlesProcoagulant materials entering blood flowmalignancy tumours）（severe pancreatitis）（Reduction of anticoagulation ）（activity of platelet）Ischemic tissue damageMicroangiopathic Hemolytic Anemia）Types and Stages of DIC）Types）
病理学：7 弥散性血管内凝血
